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Table 1 Baseline characteristics of participants in the UK Biobank (n = 335,727)

From: Association between sleep duration and metabolic syndrome: linear and nonlinear Mendelian randomization analyses

 

Habitual sleep duration (hours)

4

5

6

7 or 8

9

10

11

No. of participants

2795

13,928

63,087

230,721

20,115

4650

431

Demographics

       

 Age (years), mean (SD)

57.2 ± 7.6

57.3 ± 7.7

56.7 ± 7.8

56.7 ± 8.1

59.1 ± 7.8

59.1 ± 7.8

57.5 ± 8.2

 Male (%)

1216 (43.5)

6109 (43.9)

30,412 (48.2)

107,029 (46.4)

8835 (43.9)

2131 (45.8)

190 (44.1)

 University or college degree (%)

378 (13.5)

2748 (19.7)

17,803 (28.2)

76,579 (33.2)

4902 (24.4)

841 (18.1)

85 (19.7)

 Current smoker (%)

514 (18.4)

1986 (14.3)

7321 (11.6)

21,165 (9.2)

2068 (10.3)

677 (14.6)

67 (15.5)

 Current employed (%)

1138 (40.7)

7358 (52.8)

38,932 (61.7)

134,692 (58.4)

7030 (34.9)

1141 (24.5)

83(19.3)

 Frequent drinkera (%)

845 (30.2)

5228 (37.5)

27,656 (43.8)

108,307 (46.9)

8745 (43.5)

1775 (38.2)

128 (29.7)

 Townsend deprivation indexb, mean (SD)

– 0.1 ± 3.5

– 0.8 ± 3.3

– 1.4 ± 3.0

– 1.7 ± 2.8

– 1.6 ± 3.0

– 0.8 ± 3.3

– 0.7 ± 3.4

 Body mass index (kg/m2), mean (SD)

28.9 ± 5.7

28.3 ± 5.2

27.8 ± 4.9

27.1 ± 4.6

27.8 ± 4.9

28.9 ± 5.6

28.7 ± 5.8

Outcomes

       

 MetS (%)

1159 (41.5)

5179 (37.2)

20,205 (32.0)

66,381 (28.8)

7642 (38.0)

2221 (47.8)

212 (49.2)

Components of MetS

       

 Central obesity (%)

1283 (45.9)

5681 (40.8)

22,679 (35.9)

72,522 (31.4)

7765 (38.6)

2269 (48.8)

214 (49.7)

 High blood pressure (%)

1921 (68.7)

9718 (69.8)

42,188 (66.9)

150,652 (65.3)

14,222 (70.7)

3389 (72.9)

306 (71.0)

 Dyslipidemia (%)

732 (26.2)

3245 (23.3)

12,992 (20.6)

43,848 (19.0)

4702 (23.4)

1390 (29.9)

143 (33.2)

 Hypertriglyceridemia (%)

1586 (56.7)

7477 (53.7)

31,362 (49.7)

109,253 (47.4)

11,285 (56.1)

2911 (62.6)

276 (64.0)

 Hyperglycemia (%)

345 (12.3)

1428 (10.3)

5111 (8.1)

15,939 (6.9)

2064 (10.3)

757 (16.3)

77 (17.9)

  1. MetS: Metabolic syndrome; SD: Standard deviation
  2. aLower income was defined as average total household income before tax less than 18,000
  3. bTownsend deprivation index was calculated based on the preceding national census output areas prior to participant joining UK Biobank. Each participant is assigned a score corresponding to their postcode location with a lower score indicating lower level of social deprivation
  4. This table shows all the baseline covariates associated with sleep duration, with P < 0.001 for trend across different stratification
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Journal of Translational Medicine

ISSN: 1479-5876

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