Fig. 4

HMGB1 promoted malignancy of cancer cell through activating EMT process, and Wnt and ERK signaling. A, B The expressions of EMT process, and Wnt and ERK signaling were detected using western blot assay in SW480 cells. Data were presented as mean ± SD and each assay was performed for three times. ^*P < 0.05; ^**P < 0.01; ^***P < 0.001