Fig. 9
From: Predisposition to cortical neurodegenerative changes in brains of hypertension prone rats
Model of the molecular neurodegeneration machinery in hypertension in the SBH/y(HSD) strain after salt loading. Genetic predisposition to salt-sensitive hypertension is associated with cortical cellular dysfunction in gene transcription regulation, autophagy, stress, and apoptotic processes. These cellular dysfunctions are exacerbated by salt loading that induces concurrently hypertension. mRNA is denoted by gray, protein by light blue, and together by gold, hypertension effect denoted by a red heart