Fig. 3

Oncogenic β-catenin elevates cellular LIP. A, Representative confocal images of WT and β-catenin^Δ(ex3)/+ MEFs using iron-sensitive fluorescent PGSK dye. B–F, Flow cytometry analysis of PGSK intensity in WT and β-catenin^Δ(ex3)/+ MEFs (B); β-catenin^Δ(ex3)/+ MEFs treated with DMSO or 20 μM pri-724 for 48 h (C); 7 hepatic cancer cell lines (D); HuH7 and SNU886 transfected with vector or β-catenin^mut plasmid (E); HepG2, MHCC97H and Hepa 1–6 treated with DMSO or 20 μM pri-724 for 48 h (F); n = 3. Data were shown as mean ± SD and analysis was performed using t test. *p < 0.05, ***p < 0.001