Fig. 7From: ADAM12 promotes clear cell renal cell carcinoma progression and triggers EMT via EGFR/ERK signaling pathwayADAM12 promoted the growth of ccRCC cells in vivo. A, B ACHN cells stably infected with shADAM12 or OE-ADAM12 were injected subcutaneously into the axilla of nude mice (n = 6 for each group) to create a xenograft tumor model. The tumor growth curves were documented according to the measurement of tumor volume every 3 days, and the tumor weight was measured. C, D Representative immunohistochemistry images of xenograft tumor tissues for HE, ADAM12, c-Myc, E-cadherin, N-cadherin and Snail stainingBack to article page