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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: ADAM12 promotes clear cell renal cell carcinoma progression and triggers EMT via EGFR/ERK signaling pathway

Fig. 3

ADAM12 facilitated migration and invasion and induced EMT in ccRCC cells. A, B Wound healing assay showed the migration capacity of ccRCC cells infected with the indicated lentivirus. C, D Transwell assay revealed that the invasive capacity of ccRCC cells was obviously inhibited or strengthened after depletion or restoration of ADAM12 in ccRCC cells, respectively. E The effect of ADAM12 knockdown on EMT marker expression was assessed by western blotting. F The effect of ADAM12 overexpression on EMT marker expression in ACHN and CAKI-2 cells

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Journal of Translational Medicine

ISSN: 1479-5876

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