Fig. 7

Exploration of the differences in immune infiltration and chemotherapy response. A Bubble chart illustrating the mean abundance of the more significant (Wilcoxon test, p < 0.01) tumor-infiltrating immune and cancer cell types between Cluster 2 (blue dots) and Cluster 4 (red dots). For each data point the mean values are represented in log10 form. B–D Evaluation of the sensitivity of chemotherapy drugs between the Cluster 2 Cluster 4 based on the IC50 values of Entinostat (B), Olaparib (C), and BI-D1870 (D), for Luminal breast cancer patients