Skip to main content

Table 1 Clinicopathological characteristics of high- and low-Fut2 expression groups

From: Intestinal epithelium-specific Fut2 deficiency promotes colorectal cancer through down-regulating fucosylation of MCAM

Characteristic

Low expression of Fut2

High expression of Fut2

p

n

239

239

 

Age, n (%)

  

0.113

  <  = 65

88 (18.4%)

106 (22.2%)

 

  > 65

151 (31.6%)

133 (27.8%)

 

Gender, n (%)

  

1.000

 Female

113 (23.6%)

113 (23.6%)

 

 Male

126 (26.4%)

126 (26.4%)

 

Race, n (%)

  

0.026

 Asian

2 (0.7%)

9 (2.9%)

 

 Black or African American

39 (12.7%)

24 (7.8%)

 

 White

124 (40.5%)

108 (35.3%)

 

T stage, n (%)

  

0.426

 T1

4 (0.8%)

7 (1.5%)

 

 T2

39 (8.2%)

44 (9.2%)

 

 T3

161 (33.8%)

162 (34%)

 

 T4

35 (7.3%)

25 (5.2%)

 

N stage, n (%)

  

0.168

 N0

133 (27.8%)

151 (31.6%)

 

 N1

56 (11.7%)

52 (10.9%)

 

 N2

50 (10.5%)

36 (7.5%)

 

M stage, n (%)

  

0.021

 M0

165 (39.8%)

184 (44.3%)

 

 M1

42 (10.1%)

24 (5.8%)

 

Pathologic stage, n (%)

  

0.078

 Stage I

38 (8.1%)

43 (9.2%)

 

 Stage II

85 (18.2%)

102 (21.8%)

 

 Stage III

68 (14.6%)

65 (13.9%)

 

 Stage IV

42 (9%)

24 (5.1%)

 

Primary therapy outcome, n (%)

  

0.186

 PD

12 (4.8%)

13 (5.2%)

 

 SD

2 (0.8%)

2 (0.8%)

 

 PR

10 (4%)

3 (1.2%)

 

 CR

96 (38.4%)

112 (44.8%)

 

Age, median (IQR)

70 (58, 77)

68 (59, 78)

0.696

  1. Bold values denote two-sided p < 0.05
  2. Fut2 Fucosyltransferase 2, PD partial response, SD stable disease, PR partial response, CR complete response