Fig. 7
Fut2 inhibits colon cancer via fucosylation of MCAM. A, B The typical image and corresponding statistical results of transwell migration or invasion assay in control and MCAM overexpression SW480 cell line with Fut2 overexpressed (with or without peracetylated 2-F-Fuc treated). C Wound-healing assay at 48 h in control and MCAM overexpression SW480 cell line with Fut2 overexpressed (with or without peracetylated 2-F-Fuc treated). D The CCK8 assay at different time points (24 h, 48 h and 72 h) in control and MCAM overexpression SW480 cell line with Fut2 overexpressed (with or without peracetylated 2-F-Fuc treated). Data are expressed as mean ± SEM. The data come from three independent experiments. In all panels: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. (MCAM melanoma cell adhesion molecule, CCK8 Cell Counting Kit-8, 2-F-Fuc 2-fluorofucose, SEM Standard Error of Mean)