Table 1 Clinical findings and skeletal muscle parameters of patients with NSCLC (non-small cell lung cancer) with low- and high-muscularity defined by pectoralis muscle cross-sectional area assessed using computed tomography and classification predictive model

Age

68.5 (9.5)

69 (11)

63 (4)

67 (6)

U test

PMA (cm²)

30.3 (9.3)

37.9 (16.4)

23.9 (8.4)

32.1 (13.3)

U test

BMI (kg/m²)

21.8 (6.3)

26.5 (5.5)

–

–

U test

SMI (cm²/m²)

43.3 (6.8)

50.7 (10)

–

–

U test

PMA-SMI (cm²/m²)

9.8 (2.4)

13.3 (2.91)

–

–

Gender (%)

 Male

72.7

61.2

68.4

35.3

Chi-square

 Female

27.3

38.8

31.6

64.7

Ethnicity (%)

 Caucasian

72.7

55.3

–

–

Chi-square

 Asian

4.5

16.5

–

–

 African American

4.5

1.2

–

–

 Hispanic/Latino

0

3.5

–

–

 Native Hawaiian

4.5

1.2

–

–

 NA

13.6

22.3

–

–

Smoking history (%)

 Current

36.4

10.7

100

70.6

Chi-square

 Former

50

66.7

–

–

 Nonsmoker

13.6

22.6

0

29.4

Histology (%)

 Adenocarcinoma

72.7

85.7

63.1

41.2

Chi-square

 Squamous cell carcinoma

27.3

14.3

36.8

58.8

Stage (%)

 I–II

94.7

93.6

73.7

58.8

Chi-square

 III–IV

5.3

6.4

26.3

41.2

Grade (%)

 G1

21

37.9

23.5

42.8

Chi-square

 G2

47.4

56.1

70.6

51.2

 G3

31.6

6

5.9

–

Lymphovascular invasion (%)

 Yes

11.8

5

Chi-square

 No

88.2

95

73.7

68.7

Pleural invasion (%)

26.3

31.3

 Yes

31.6

12.3

58.8

40

Chi-square

 No

68.4

87.7

41.2

60

Recurrence (%)

 Yes

36.4

14.3

42.1

23.5

Chi-square

 No

63.6

85.7

57.8

76.5

EGFR mutation status (%)

 Wildtype

82.3

71

–

–

Chi-square

 Mutant

17.7

29

–

–

KRAS mutation status (%)

 Wildtype

68.7

83.1

–

–

Chi-square

 Mutant

31.3

16.9

–

–