Fig. 6

MT alleviates nTreg mitochondria functional and structural damage induced by cholesterol. In vitro expanded nTregs were treated with cholesterol alone or in combination with MT for 16 h. A, B OCR of nTregs was measured by Seahorse assay. n = 5 per group. C, D The glycoPER of nTregs was measured by Seahorse assay. n = 5 per group. E The mitochondrial number and structure of nTregs were examined with transmission electron microscopy. Data are expressed as the mean ± SEM. *P < 0.05, **P < 0.01