Fig. 7

Propranolol alleviated ATO-induced apoptosis in mouse cardiomyocytes and myocardial tissues. A Representative flow cytometry images. B Statistical analysis of the flow cytometry results. C Representative TUNEL staining images of mouse cardiomyocytes. Magnification: 200 × ; scale bar: 100 μm. D Propranolol decreased Bax protein expression in ATO-treated mouse cardiomyocytes. E Propranolol increased Bcl-2 protein expression in ATO-treated mouse cardiomyocytes. F Representative TUNEL staining images of mouse myocardial tissues. Magnification: 400 × ; scale bar: 40 μm. G Propranolol decreased Bax protein expression in ATO-treated mouse myocardial tissues. H Propranolol increased Bcl-2 protein expression in ATO-treated mouse myocardial tissues. For B, D, E, G and H, one-way ANOVA F value = 709, 11.64, 41.51, 8.302 and 5.311, respectively. *P < 0.05, **P < 0.01, ***P < 0.001 vs. control group; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. ATO group; n = 3–6