Table 1 Clinical characteristics of the participants
From: Alterations in the human oral microbiota in systemic lupus erythematosus
Clinical indices | Derivation | P valuea | Validation | P valuea | P valueb | ||
|---|---|---|---|---|---|---|---|
SLE (n = 100) | HCs (n = 200) | SLE (n = 40) | HCs (n = 80) | ||||
Age | 34 (25, 41.75) | 32 (28, 38.75) | 0.1004 | 33 (27, 43) | 31.5 (28, 35) | 0.3096 | 0.7533 |
Gender (F/M) | 94/6 | 184/16 | 0.5310 | 37/3 | 75/5 | 0.7958 | 0.7437 |
BMI (Kg/m2) | 21.81 (19.50, 24.13) | 22.05 (20.88, 23.16) | 0.9682 | 21.10 (19.08, 24.59) | 21.94 (21.03, 23.22) | 0.0626 | 0.1836 |
WBC (× 109/L) | 5.08 (3.98, 6.72) | 5.90 (5.10, 7.10) |  < 0.0001 | 4.78 (3.67, 6.85) | 6.40 (5.3, 7.4) | 0.0009 | 0.7711 |
RBC (× 1012/L) | 4.02 ± 0.53 | 4.71 ± 0.49 |  < 0.0001 | 3.99 ± 0.64 | 4.78 ± 0.44 |  < 0.0001 | 0.8553 |
Hb (g/L) | 120.2 ± 17.81 | 138.2 ± 16.02 |  < 0.0001 | 118.2 ± 19.95 | 145.8 ± 13.8 |  < 0.0001 | 0.6617 |
Plt (× 109/L) | 201 (162.8, 257.8) | 235 (201.5, 265) | 0.0002 | 180 (127, 256) | 241 (212, 269) | 0.0006 | 0.2520 |
Lyn# (× 109/L) | 1.23 (0.85, 1.56) | 1.99 (1.66, 2.38) |  < 0.0001 | 1.31 (0.85, 1.82) | 2.07 (1.84, 2.49) |  < 0.0001 | 0.4767 |
Glb (g/L) | 29.6 (26.5, 33.7) | 26.8 (24.5, 28.9) |  < 0.0001 | 31.45 (26.15, 35.73) | 26.10 (24.05, 28.65) |  < 0.0001 | 0.4415 |
C3 (0.9–1.8 g/L) | 0.82 (0.66, 1.01) | – | – | 0.82 (0.71, 1.10) | – | – | 0.3943 |
C4 (0.1–0.4 g/L) | 0.14 (0.11, 0.20) | – | – | 0.15 (0.11, 0.20) | – | – | 0.9328 |
Anti-dsDNA (0–100 IU/mL) | 198 (15.48, 779) | – | – | 120.9 (16.25, 686) | – | – | 0.7627 |
Disease activity | Â | Â | Â | Â | Â | Â | Â |
Mild/moderate/severe | 50/41/9 | – | – | 18/17/5 | – | – | 0.5190 |