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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Tanshinone IIA ameliorates Aβ transendothelial transportation through SIRT1-mediated endoplasmic reticulum stress

Fig. 3

Tan IIA ameliorates cognitive deficits in APP/PS1 mice. a Schedule of animal treatments and behavior tests. b-f Morris water maze test: b Escape latency. c Behavioral trajectories. d Crossing times in the quadrant of fixed platform. e Time spent in the quadrant of fixed platform. f The swimming speed. New object recognition test: g Behavioral trajectories. h The recognition index. Open field test: i Behavioral trajectories. j The central region distance. Tan-L: Tan IIA (10 mg/kg/d); Tan-H: Tan IIA (20 mg/kg/d). The mean ± SD was calculated based on ten separate studies. *P < 0.05, **P < 0.01, NS: no significance

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