Fig. 4
From: Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging
The system role of MOTS-c. MOTS-c acts on multiple systems such as muscle, adipose tissue and immune system through blood circulation. MOTS-c can increase muscle's motor function and insulin sensitivity, promote the conversion from white adipose tissue to brown adipose tissue while activating brown adipose tissue, additionally decreasing the expression of inflammatory factors and increasing the anti-inflammatory effect. Besides, MOTS-c is beneficial for antioxidant stress, metabolic homeostasis, exercise capacity and healthy aging