Fig. 7From: Transcriptomic analyses of treatment-naïve pediatric ulcerative colitis patients and exploration of underlying disease pathogenesisIL-1α promotes intestinal inflammation and fibrotic activity in pediatric UC. A, B Caco2 cells were treated with IL-1α (20 ng/ml) for 8 h, and then RNA was collected to assess COL6A3 and MMP12 expression by qPCR. C A diagram representing the mechanisms driving intestinal inflammation and fibrosis in pediatric UCBack to article page