Table 8 The top 20 drugs interacting with CYP3A4
Rank | Drug name | DrugBank ID | Evidence | Rank | Drug name | DrugBank ID | Evidence |
|---|---|---|---|---|---|---|---|
1 | Amitriptyline | DB00321 | Confirmed | 11 | Ketamine | DB01221 | Confirmed |
2 | Haloperidol | DB00502 | Confirmed | 12 | Enflurane | DB00228 | N.A |
3 | Brigatinib | DB12267 | Confirmed | 13 | Melatonin | DB01065 | N.A |
4 | Aripiprazole | DB01238 | Confirmed | 14 | Nandrolone decanoate | DB08804 | N.A |
5 | Methadone | DB00333 | Confirmed | 15 | Glycyrrhizic acid | DB13751 | N.A |
6 | Pyrimethamine | DB00205 | N.A | 16 | Dabrafenib | DB08912 | Confirmed |
7 | Rhein | DB13174 | Confirmed | 17 | Naringenin | DB03467 | N.A |
8 | Olaparib | DB09074 | Confirmed | 18 | Tenofovir disoproxil | DB00300 | N.A |
9 | Ponatinib | DB08901 | Confirmed | 19 | Tepotinib | DB15133 | Confirmed |
10 | Zanubrutinib | DB15035 | Confirmed | 20 | Nilotinib | DB04868 | Confirmed |