Table 1 The details of the DTIs gold standard datasets added other heterogeneous information
Data set | Interaction types | # of entity A | # of entity B | # of edge A-B |
|---|---|---|---|---|
Enzymes | Protein–drug Interaction | 662 | 445 | 2923 |
Drug-Drug Interaction | 248 | 248 | 6598 | |
Drug-Disease Association | 356 | 3174 | 80,943 | |
GPCRs | Protein–drug Interaction | 95 | 223 | 635 |
Drug-Drug Interaction | 133 | 133 | 2775 | |
Drug-Disease Association | 188 | 5257 | 80,077 | |
Ion channels | Protein–drug Interaction | 204 | 210 | 1476 |
Drug-Drug Interaction | 115 | 115 | 2875 | |
Drug-Disease Association | 183 | 4438 | 65,951 | |
Nuclear receptors | Protein–drug Interaction | 26 | 54 | 90 |
Drug–drug Interaction | 43 | 43 | 254 | |
Drug-Disease Association | 49 | 5509 | 50,032 | |
proDB | Protein–drug Interaction | 3004 | 3945 | 20,808 |
Drug-Drug Interaction | 1626 | 1626 | 194,264 | |
Drug-Disease Association | 2485 | 7085 | 2,028,072 |