Table 5 Correlation between HLA-DPA1 and CD4 expression and the infiltration of immune cells in HNSCC from GSCA
Cancer | Symbol | Cell type | Cor | p_value | Fdr |
|---|---|---|---|---|---|
HNSC | CD4 | Bcell | 0.125229401 | 0.002840681 | 0.00709747 |
HNSC | CD4 | CD4_T | 0.498597147 | 6.63574E-37 | 2.34323E-35 |
HNSC | CD4 | CD4_naive | −0.32641244 | 1.61664E-15 | 2.27551E-13 |
HNSC | CD4 | CD8_T | 0.487711864 | 3.70562E-35 | 2.41381E-33 |
HNSC | CD4 | CD8_naive | −0.27974378 | 1.23245E-11 | 3.86398E-10 |
HNSC | CD4 | Central_memory | 0.399107546 | 4.69625E-23 | 1.75049E-21 |
HNSC | CD4 | Cytotoxic | 0.648867218 | 6.05612E-69 | 6.66107E-67 |
HNSC | CD4 | DC | 0.264792464 | 1.55096E-10 | 1.81922E-09 |
HNSC | CD4 | Effector_memory | −0.348009036 | 1.47439E-17 | 3.6235E-16 |
HNSC | CD4 | Exhausted | 0.430230051 | 6.61951E-27 | 3.14239E-25 |
HNSC | CD4 | Gamma_delta | 0.350506267 | 8.36139E-18 | 1.3932E-16 |
HNSC | CD4 | InfiltrationScore | 0.774932647 | 1.8103E-114 | 6.1759E-112 |
HNSC | CD4 | MAIT | −0.079904273 | 0.057456885 | 0.102199733 |
HNSC | CD4 | Macrophage | 0.623132464 | 3.43057E-62 | 7.75849E-60 |
HNSC | CD4 | Monocyte | 0.026849971 | 0.52380974 | 0.648854849 |
HNSC | CD4 | NK | 0.452353693 | 6.74773E-30 | 3.80443E-28 |
HNSC | CD4 | NKT | −0.069342829 | 0.099341311 | 0.161500841 |
HNSC | CD4 | Neutrophil | −0.734956861 | 3.26494E-97 | 7.73137E-95 |
HNSC | CD4 | Tfh | 0.61809823 | 6.07528E-61 | 5.07399E-59 |
HNSC | CD4 | Th1 | 0.400553951 | 3.17398E-23 | 1.31996E-21 |
HNSC | CD4 | Th17 | −0.522771785 | 5.12345E-41 | 7.99417E-39 |
HNSC | CD4 | Th2 | 0.151716151 | 0.000291823 | 0.001462605 |
HNSC | CD4 | Tr1 | 0.526495547 | 1.11241E-41 | 2.11779E-39 |
HNSC | CD4 | iTreg | 0.578673885 | 6.65288E-52 | 2.15983E-49 |
HNSC | CD4 | nTreg | 0.132102751 | 0.001634437 | 0.004873403 |
HNSC | HLA-DPA1 | Bcell | 0.160458983 | 0.000126143 | 0.000439536 |
HNSC | HLA-DPA1 | CD4_T | 0.390194718 | 5.0338E-22 | 5.91479E-21 |
HNSC | HLA-DPA1 | CD4_naive | −0.341193739 | 6.75694E-17 | 1.51115E-14 |
HNSC | HLA-DPA1 | CD8_T | 0.571758553 | 1.92463E-50 | 2.54861E-48 |
HNSC | HLA-DPA1 | CD8_naive | −0.353117464 | 4.59558E-18 | 6.00057E-16 |
HNSC | HLA-DPA1 | Central_memory | 0.317720549 | 9.66095E-15 | 1.05282E-13 |
HNSC | HLA-DPA1 | Cytotoxic | 0.718927306 | 3.78606E-91 | 9.64631E-89 |
HNSC | HLA-DPA1 | DC | 0.170909511 | 0.000043664 | 0.000157248 |
HNSC | HLA-DPA1 | Effector_memory | −0.142157787 | 0.000694338 | 0.001711443 |
HNSC | HLA-DPA1 | Exhausted | 0.527673099 | 6.83588E-42 | 8.82004E-40 |
HNSC | HLA-DPA1 | Gamma_delta | 0.399847288 | 3.84448E-23 | 1.39931E-21 |
HNSC | HLA-DPA1 | InfiltrationScore | 0.6560327 | 6.07356E-71 | 6.57251E-69 |
HNSC | HLA-DPA1 | MAIT | −0.069344284 | 0.099334199 | 0.161528417 |
HNSC | HLA-DPA1 | Macrophage | 0.482428439 | 2.47987E-34 | 1.81509E-32 |
HNSC | HLA-DPA1 | Monocyte | −0.170950179 | 0.000043478 | 0.000248193 |
HNSC | HLA-DPA1 | NK | 0.545950055 | 2.77657E-45 | 4.17066E-43 |
HNSC | HLA-DPA1 | NKT | −0.11742411 | 0.005156123 | 0.012552302 |
HNSC | HLA-DPA1 | Neutrophil | −0.72886484 | 7.40981E-95 | 1.60371E-92 |
HNSC | HLA-DPA1 | Tfh | 0.636744419 | 1.10534E-65 | 1.08002E-63 |
HNSC | HLA-DPA1 | Th1 | 0.549856923 | 4.91135E-46 | 6.21734E-44 |
HNSC | HLA-DPA1 | Th17 | −0.493278817 | 4.82249E-36 | 4.78163E-34 |
HNSC | HLA-DPA1 | Th2 | 0.188362098 | 6.42744E-06 | 0.000064815 |
HNSC | HLA-DPA1 | Tr1 | 0.327139515 | 1.38843E-15 | 1.57711E-14 |
HNSC | HLA-DPA1 | iTreg | 0.493931466 | 3.78772E-36 | 3.23048E-34 |
HNSC | HLA-DPA1 | nTreg | 0.127127138 | 0.002444997 | 0.006899699 |