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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Splicing factor-mediated regulation patterns reveals biological characteristics and aid in predicting prognosis in acute myeloid leukemia

Fig. 1

Genetic characteristics of SFs in hnRNP and SR families in AML samples. A The heatmap depicts the difference in SFs expression between AML samples and normal samples. B Somatic mutations in SFs in 134 TCGA-LAML patient samples; Each column in the waterfall plot represents the mutation type for each patient, the tumor mutation burden (TMB) for each patient is shown in the top half, the mutation frequency and mutation type ratio of SFs are shown on the right, and the proportion of different base transitions is shown below. C Copy number variation frequency of SFs. D The position of SFs on 23 chromosomes (*P < 0.05; **P < 0.01; ***P < 0.001)

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