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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1

Fig. 6

The anti-osteosarcoma effects of Aa-Z2 in vivo. A, B Representative images of nude mice and xenograft tumours. C The tumour weight of xenograft tumours. D Tumour volume curve of xenograft tumours. E Representative pictures of H&E and IHC staining for Ki-67 and Cle-caspase 3 in xenograft tumours. F, G Comparison of Ki-67- and Cle-caspase 3- positive cells among the 3 groups. H Mice’s body weight curve. I Representative images of H&E staining of the heart, liver, kidney and lung. Mean ± SD (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001)

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