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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Panomics reveals patient individuality as the major driver of colorectal cancer progression

Fig. 1

Unsupervised principal component analysis (a) and volcano plots of differentially expressed genes between all three group comparisons for NM, T, and LM (bd). The PCA plot displays all four individual patients (P1, blue; P2, yellow; P3, purple; P4, grey). The X- and y-axes show the first and second principal components, respectively. Volcano plots are presented with the fold-change of the corresponding comparison in logarithmic scale (x-axis) against the q-value (y-axis) of b tumour vs. normal mucosa, c metastasis vs. normal mucosa, and d metastasis vs. tumour comparisons. Significance thresholds (q-value < 0.01 and |log2FC| threshold of > 2) are indicated by dashed lines. Genes passing these cut-offs were considered significant and coloured in yellow. Genes passing the q-value but not the log2FC threshold are coloured in rose. Genes that were not significant but passed the log2FC threshold are indicated in blue

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