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Table 1 Characteristic of the study population (n = 2959)

From: Hyperuricemia as an effect modifier of the association between metabolic phenotypes and nonalcoholic fatty liver disease in Chinese population

 

MHNW (n = 835)

MHO (n = 878)

MUNW (n = 312)

MUO (n = 934)

P

Age, years

50.24 ± 16.64

52.12 ± 15.70a

65.76 ± 15.70a,b

58.41 ± 15.26a,b,c

 < 0.001

Sex

 Male

432 (51.74)

683 (77.79)

209 (66.99)

764 (81.80)

 < 0.001

 Female

403 (48.26)

195 (22.21)

103 (33.01)

170 (18.20)

 

BMI, kg/m2

21.81 ± 1.44

26.46 ± 2.08a

22.51 ± 1.21a,b

27.39 ± 2.63a,b,c

 < 0.001

SBP, mmHg

121.55 ± 16.21

129.33 ± 16.92a

141.65 ± 16.71a,b

141.92 ± 16.19a,b

 < 0.001

DBP, mmHg

69.95 ± 9.87

75.34 ± 10.46a

77.01 ± 11.05a

81.68 ± 11.65a,b,c

 < 0.001

Total cholesterol, mmol/L

5.29 ± 0.96

5.27 ± 0.97

5.49 ± 1.13a,b

5.45 ± 1.09a,b

 < 0.001

Triglyceride, mmol/L

1.16 ± 0.48

1.39 ± 0.61a

2.01 ± 1.13a,b

2.53 ± 1.77a,b,c

 < 0.001

HDL-C, mmol/L

1.55 ± 0.32

1.39 ± 0.27a

1.28 ± 0.31a,b

1.17 ± 0.23a,b,c

 < 0.001

LDL-C, mmol/L

3.02 ± 0.78

3.20 ± 0.79a

3.22 ± 0.87a

3.24 ± 0.84a

 < 0.001

FBG, mmol/L

4.87 ± 0.70

4.97 ± 0.68

6.07 ± 2.25a,b

5.96 ± 1.84a,b

 < 0.001

Creatinine, μmol/L

62.98 ± 17.91

68.52 ± 14.77a

67.05 ± 18.56a

70.60 ± 29.85a,b,c

 < 0.001

Uric acid, μmol/L

328.58 ± 82.98

383.65 ± 90.02a

358.95 ± 95.66a,b

403.16 ± 90.89a,b,c

 < 0.001

ALT, U/L

16.00

(12.00–22.00)

20.00a

(16.00–29.00)

19.00a,b

(14.00–25.00)

25.00a,b,c (18.00–37.00)

 < 0.001

Total bilirubin, μmol/L

13.00 (10.40–16.20)

13.50 (10.58–16.80)

12.70 (10.30–16.00)

13.20 (10.40–16.90)

0.064

Albumin, g/L

43.79 ± 2.89

43.56 ± 2.47

43.69 ± 3.24

43.77 ± 3.44a

0.357

  1. Data are presented as mean ± standard deviations, or number (proportion %)
  2. MHNW metabolically healthy normal weight, MHO metabolically healthy obesity, MUNW metabolically unhealthy normal weight, MUO metabolically unhealthy obesity, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL-C high density lipoprotein, LDL-C low density lipoprotein, FBG fasting blood glucose, ALT alanine transaminase
  3. aCompared to MHNW group, the difference was statistically significant
  4. bCompared to MHO group, the difference was statistically significant
  5. cCompared to MUNW group, the difference was statistically significant