Table 2 Univariate and multivariate Cox regression model built to predict PFS including the genetic score and clinical characteristics of PCa patients
Variable | Univariate | Multivariate | |||
|---|---|---|---|---|---|
HR (95% CI) | p-value | HR (95% CI) | p-value | ||
Glucose-metabolism-related genetic score | < 0.1511 | 1.00 (ref) | – | 1.00 (ref) | – |
≥ 0.1511 | 3.42 (2.15–5.45) | < 0.0001 | 2.81 (1.69–4.62) | < 0.0001 | |
Age at diagnosis (years) | < 61 | 1.00 (ref) | – | ||
≥ 61 | 1.62 (0.77–1.74) | 0.469 | |||
Race | White | 1.00 (ref) | – | ||
Black or African American | 0.001 (0.001–255.10) | 0.957 | |||
Histopathological tumour type | Acinar | 1.00 (ref) | – | ||
Other type | 2.04 (0.74–5.57) | 0.162 | |||
T-status | < T2c | 1.00 (ref) | – | 1.00 (ref) | – |
≥ T3a | 3.69 (2.09–6.54) | < 0.0001 | 3.06 (1.61–5.85) | 0.0007 | |
N-status | 0 | 1.00 (ref) | – | ||
1 | 1.81 (1.11–2.96) | 0.016 | |||