Fig. 7

ICIs, immune escape, and PPI network. A–C TIDE score, exclusion score, and dysfunction score were significantly higher for the high EMVI score group than for the low EMVI score group. D Patients with a high EMVI score had a lower response rate to ICIs therapy (PDL1). E, F The low EMVI score group had higher microsatellite instability (MSI). G Through using correlation analysis, we found that EMVI scores were positively correlated with 8 EMVI proteins. H, I PPI network for EMVI-related genes showed that CXCL12 and SOX17 were at the core of the network. MSS: microsatellite stable group, L-MSI: low MSI group; H-MSI: high MSI group. *P < 0.05; *** P < 0.001