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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Angiotensin-(1–7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways

Fig. 3

Ang-(1–7) attenuates inflammatory response, macrophage infiltration, and oxidative stress in myocardial tissues of the SIC mice. A Representative immunofluorescence images of macrophage infiltration in myocardial tissue of each group (20 μm; × 400, scale bar). B Number of F4/80+ macrophages (n = 4). CG The IL-6, Ang II, TNF-α, Ang-(1–7), and IL-1β protein concentrations in the myocardial specimens (n = 6). HJ TNF-α, IL-1β, and IL-6 mRNA levels in myocardial tissue samples (n = 4). K Images showing the DHE staining in myocardial tissues (50 μm; × 200, scale bar). L Relative fluorescence intensity of the DHE procedure (n = 4). *p < 0.05, **p < 0.01, ***p < 0.001

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