Fig. 6From: Alamandine/MrgD axis prevents TGF-β1-mediated fibroblast activation via regulation of aerobic glycolysis and mitophagyALA upregulated Parkin/LC3B-mediated mitophagy to repress lung fibroblast activation. A–C Protein levels of LC3BII in cell lysate and mitochondrial components. D–F Collagen I and α-SMA were assessed after treatment with 3MA (10 μmol/L), parkin siRNA, or Mdivi-1 (10 μmol/L). Data are presented as mean ± SEM. *P < 0.05 versus control group; #P < 0.05 versus TGF-β1 group; △P < 0.05 versus TGFβ1 + ALA group; &P < 0.05 versus TGFβ1 + ALA + bafilomycin A1 group (n = 3)Back to article page