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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy

Fig. 4

Correlations between SpHe-comut status and immune response-related gene mRNA expression. A Heatmap of mean expression differences in immune response-related genes between SpHe-comut+ and SpHe-comut− patients across different cancer types. B–E Comparison of the expression levels of genes related to the tumour microenvironment (B), immune checkpoints (C), T-cell receptor (D), and INFγ pathway and T-effector (E) signature between SpHe-comut+ and SpHe-comut− groups in the pan-cancer analysis. *FDR < 0.05; **FDR < 0.01; ***FDR < 0.001; ****FDR < 0.0001; *****FDR < 0.00001.

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