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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Downregulation of SMIM3 inhibits growth of leukemia via PI3K-AKT signaling pathway and correlates with prognosis of adult acute myeloid leukemia with normal karyotype

Fig. 4

Apoptosis and cell cycle analysis in AML cell lines. A, B The flow cytometry was applied to analyze apoptosis in SMIM3 knockdown cells compared with control. C–E Propidium iodide (PI) staining was applied to analyze the cell cycle of SMIM3 knockdown cells compared with control. F Alterations in apoptosis and cell cycle-related protein assay in SMIM3 knockdown cells compared with control. G, H Densitometric analysis of the WB signals. CTRL, control; KD, knockdown; *P < 0.05 compared with CTRL cells; **P < 0.01 compared with CTRL cells; ***P < 0.001 compared with CTRL cells

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