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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Uncovering the gene regulatory network of type 2 diabetes through multi-omic data integration

Fig. 4

Validation of key drivers. A RT-qPCR analysis of the mRNA expression levels of CD74 and PSMB9 between T2D and control. B The GSE25724 dataset was used to validate the diagnostic effectiveness of the biomarkers for T2D by ROC analysis. C Protein expression of 3 key drivers (PSMB9, COL1A1, and COL4A1) in T2D and control. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 with comparisons indicated by lines. RT-qPCR reverse transcription-quantitative PCR, ns not significant

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