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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Integrative metagenomic and metabolomic analyses reveal the role of gut microbiota in antibody-mediated renal allograft rejection

Fig. 3

Changes in fecal metabolites in AMR after kidney transplantation. The LC/MS-based untargeted metabolic profiling in positive and negative mode was conducted on fecal samples. A OPLS-DA score plots of fecal metabolite profiles derived from recipients with AMR and controls in positive mode (left panel) and negative mode (right panel). B Volcano plot for the differential fecal metabolites significant changed in AMR group compared to control group (VIP > 1; P < 0.05). C Histogram illustrating the differential fecal metabolites significant changed in AMR group compared to control group (VIP > 1; P < 0.05). D Bubble diagram of metabolic pathways enrichment based on the differential metabolites between two groups. Ctrl, control; AMR, antibody-mediated rejection

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