PHF5A facilitates the development and progression of gastric cancer through SKP2-mediated stabilization of FOS

Table 2 Relationship between PHF5A expression and tumor characteristics in patients with gastric cancer

Features	No. of patients	PHF5A expression		P value
Features	No. of patients	Low	High	P value
All patients	114	55	59
Age (years)				0.260
≤ 64	58	31	27
> 64	56	24	32
Gender				0.048
Male	79	43	36
Female	35	12	23
Tumor size				0.889
< 5 cm	48	23	25
≥ 5 cm	58	27	31
Differentiation				0.814
Low	41	19	22
Mediate	57	29	28
High	3	1	2
T Infiltrate				0.047
T1	6	4	2
T2	12	8	4
T3	73	35	38
T4	23	8	15
lymphatic metastasis (N)				0.182
N0	18	10	8
N1	16	10	6
N2	26	12	14
N3	54	23	31
Stage				0.042
I	8	5	3
II	30	18	12
III	74	32	42
IIII	2	0	2
Vessel carcinoma embolus				0.603
0	25	13	12
1	59	27	32
Nerve tumor infiltrates				0.819
0	30	14	16
1	20	10	10
Expression of Ki67				0.124
< 60%	44	25	19
≥ 60%	58	24	34
Expression of CD34				0.744
No	13	6	7
Yes	31	16	15
Expression of EGFR				0.650
No	87	43	44
Yes	14	6	8
Expression of VEGF				0.779
No	41	19	22
Yes	61	30	31
Expression of CDX2				0.281
No	18	11	7
Yes	85	40	45
Expression of Her2				0.954
No	75	37	38
Yes	26	13	13
Number of lymphatic metastases				0.134
≤ 6	58	32	26
> 6	56	23	33

ISSN: 1479-5876