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Table 2 The final validated SNP associated with positive lymph node efficacy in nasopharyngeal carcinoma patients after radiotherapy on CACNA2D3 gene

From: A two-stage genome-wide association study identifies novel germline genetic variations in CACNA2D3 associated with radiotherapy response in nasopharyngeal carcinoma

Characteristics

rs11130424

P value

OR (95%CI)

Discovery stage

8.71×10-6

2.53 (1.68-3.81)

Validation stage 1

0.046

1.26 (1.00-1.59)

Validation stage 2

1.33×10-4

2.33 (1.51-3.62)

Combined stage

1.38×10-5

1.70 (1.34-2.15)