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Table 2 Summary of the clinical characteristics of the patient groups included in the verification cohort

From: A combination of molecular and clinical parameters provides a new strategy for high-grade serous ovarian cancer patient management

 

Chemoresistant (n = 25)

Chemosensitive (n = 63)

Age (years)

Average (range)

63 (49–81)

59 (37–84)

Menopausal status (n, %)

Premenopausal

1 (4%)

18 (29%)

Postmenopausal

24 (96%)

45 (71%)

Stage (n, %)

IIIA

0

2 (3%)

IIIB

1 (4%)

6 (10%)

IIIC

16 (64%)

45 (71%)

IVA

3 (12%)

4 (6%)

IVB

5 (20%)

6 (10%)

Serum CA125 levels at diagnosis (U/mL)

Average (range)

2246 (161–10,548)

1385 (20–19,007)

TFIp (months)

Average (range)

3 (1–5)

13 (6–63)

Primary treatment (n, %)

Cytoreductive surgery

7 (28%)

44 (70%)

Neoadjuvant chemotherapy

18 (72%)

19 (30%)

Status (n, %)

Alive

0

31 (49%)

Dead

25 (100%)

32 (51%)

  1. TFIp: treatment-free interval to platinum