Fig. 1From: Genetic risk factors for ME/CFS identified using combinatorial analysisConceptual representation of features, combinations, disease signatures and communities used to build up the disease architecture in the PrecisionLife combinatorial methodology. In the case of the ME/CFS study all features were SNP genotypes, but other feature types, e.g., a patient’s expression level of a specific protein, medication history or their eosinophil level, can also be used. Circles represent features (in this case SNPs), and edges connecting them represent co-association in patients. Shaded circles represent “critical” SNPs as described in the textBack to article page