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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Kinin B1 receptor blockade attenuates hepatic fibrosis and portal hypertension in chronic liver diseases in mice

Fig. 3

BI 113823 treatment reduced the expression of fibrosis mediators in CCl4 and BDL mice livers. A, B Western blot for the protein expression of α-SMA, Col1, VEGF, PCNA, GAPDH and P-AKT, AKT, GAPDH in A CCl4 and B BDL mice livers. C, D The expression of Col1, Col2, Col4, TGF, CTGF and PDGF mRNA in C CCl4 and D BDL mice livers. Values are mean ± SEM, n = 7–8. p values indicated in panels, ns. not significant and significant as *p < 0.05; **p < 0.01; ***p < 0.001. One-way ANOVA and Tukey’s multiple comparison test were performed

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