Fig. 6

M1-type macrophage-derived exosomes reversed EMT. A–D, The levels of TNF-α (A), IL-1β (B), TGF-β (C), and IL-10 (D) in the supernatant secreted by RAW 264.7 cells treated with or without MPLA. E, The expression of E-cadherin, α-SMA and vimentin were determined in MLE-12 cells by western blot assay. F–H, Relative qualification of E-cadherin, α-SMA and vimentin expression level in MLE-12 cells after irradiation. Ns means no significantly different. *P < 0.05 vs CON group or 0 h group. **P < 0.01 vs CON group or 0 h group, *** P < 0.001 vs CON group or 0 h group, ****P < 0.0001 vs CON group or 0 h group