Fig. 3

Relationship between microbiota, short chain fatty acids, calprotectin and anthropometric, physiological and biochemical parameters. A Spearman correlation of the alpha-diversity indices, short chain fatty acids and calprotectin (separated by vertical brown lines) with anthropometric, physiological and biochemical parameters (the three groups of parameters are separated by horizontal green lines); C Spearman correlation of the bacterial abundance at the family, order, class and phylum levels (separated by horizontal green lines) with anthropometric, physiological and biochemical parameters (separated by vertical brown lines); B, D, E, F pairwise scatterplots illustrating the relationship between two variables, observed number of unique features and LPS (B), abundance of the family Coriobacteriaceae and plasma glucose (D) or PWA PP (E), abundance of order Lactobacillales and systolic blood pressure (SBP); G, H Bray-Curtis distance-based redundancy analysis (db-RDA) ordination plots with scaling focused on correlative relationships between explanatory variables and bacterial taxa (G) or metabolic pathway abundance (H). Green points represent samples (women), red arrows represent bacteria or metabolic pathways, blue arrows represent explanatory variables. In H, colored areas represent the clusters of pathways that correlate with VF or WC according to the strength and direction of the relationship: Blue: stronger positive correlation with VF, green: weaker positive correlation with VF (marked red are pathways that re-appear in an univariate analysis), yellow: negative correlation with VF, pink: negative correlation with WC, VF—visceral fat, WC—waist circumference. Mapping from FDR adjusted P values ranges to symbols: 0–0.001 '***', 0.001–0.01 '**', 0.01–0.05 '*', 0.05–0.1 '.', 0.1—1.0 no symbol, Q—FDR adjusted P, Rho—Spearman correlation coefficient; C2r—ratio of acetic acid, C3r—ratio of propionic acid; C4r—ratio of butyric acid, C5r—ratio of valeric acid, C6r—ratio of hexanoic acid (to all analyzed SCFA)