Fig. 4

CD7 CAR-T cells exhibit powerful antitumour functions in vitro A CD7 expression levels in CCRF-CEM, KG-1a, MOLM-13, K562, and K562-CD7 cells. B, D–H Specific lysis of CCRF-CEM, KG-1a, MOLM-13, K562-CD7, and K562 cells by CD7 CAR-T cells and NTR at various E:T ratios (n = 3). C, I Cytotoxic effects of CD7 CAR or NTR on primary CD7⁺ R/R-AML blasts at E:T ratios of 1:1, 2:1, and 4:1 (n = 3). J Cytokine secretion (IFN-γ, TNF-α, and IL-2) of CD7 CAR or NTR on KG-1a cells at E:T (1:1) (n = 3). ns, not significant; *P < 0.01; **P < 0.01; ***P < 0.001; ****P < 0.0001