Fig. 7

Multi-dimensional analyses uncovered the biological heterogeneity underlying SCFDS subtyping. A The ridge plot of the top KEGG terms depicted by GSEA of three subtypes. B The boxplot displays the xCell enrichment score of different cell subsets using the xCell algorithm. C Distribution of cell abundance in the microenvironment among three subtypes. D Distribution difference of the immune score, stroma score, and microenvironment score among three subtypes. E The violin plot of significant differences in the principal-component 1 score for three subtypes based on SCFDS. F The fibrosis-associated comprehensive pathway and gene set profiles of three clusters. G Distribution difference of the SMC differentiation markers expression patterns among three subtypes