Fig. 1
From: A novel murine model of combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma
Generation of spontaneous primary liver cancer model using hydrodynamic tail vein injection (HDVI) and in situ electroporation (Epo). A Schematic of plasmids designed. B Schematic of intrahepatic delivery of plasmids through HDVI or Epo. C The overall survival rate of MAPHDVI and MAPEpo mice, respectively. D Representative images of livers from mice received HDVI- or Epo-dependent plasmids via intrahepatic transfection. E Representative hematoxylin and eosin (H&E), HNF4α, and CK-19 staining of liver tissues shown in Fig. 1D. Scale bar, 200 μm