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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Urinary exosomal hsa_circ_0001250 as a novel diagnostic biomarker of idiopathic membranous nephropathy

Fig. 3

Profiling of differentially expressed urinary exosomal circRNAs of IMN and HC. A Percentage of novel and known differentially expressed circRNAs. B The counts of differentially expressed circRNAs based on their length. C The location of differentially expressed circRNAs on human chromosomes. D The distribution of differentially expressed circRNAs based on their categories. E Volcano plot of differentially expressed circRNAs between IMN and HC groups. Red dots represent circRNAs that are significantly differentially expressed. Outside the two vertical lines are the circRNAs with a Fold Change more than 2, the horizontal line indicates a p-value of 0.05. F Scatter plot of differentially expressed circRNAs in IMN and HC groups. Red and green dots indicate significant up-regulated and down-regulated circRNAs, respectively (with a fold change (FC) > 2.0 and P < 0.05). G Heatmap illustrating differentially expressed circRNAs between IMN and HC groups. The color key indicates the expression levels of circRNAs ranging from low (green) to high (red)

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