Fig. 5
From: Estrogen antagonizes ASIC1a-induced chondrocyte mitochondrial stress in rheumatoid arthritis
Estradiol treatment improved the histopathological features in ovariectomized AA rats in vivo. Representative micrographs of A H&E-stained histological sections (n = 6 per group) and B toluidine blue-stained histological sections (n = 6 per group) of the joints of ovariectomized AA rats. Representative micrographs and quantitative analysis of the immunohistochemical detection of C, F HSP10 expression (n = 6 per group), D, G ClpP expression (n = 6 per group), and E, H LONP1 expression (n = 6 per group). *P < 0.05, **P < 0.01, ***P < 0.001