Biological role of matrix stiffness in tumor growth and treatment

Table 1 Measuring method of matrix stiffness

Method	Advantages	Disadvantages
AFM	High sensitivity	Small imaging range
	High resolution imaging [125]	Slow testing speed
	Micro/nano-scale [126]	Only suitable for in vitro assays [128]
	Wide working conditions [127]	Only suitable for in vitro assays [128]
SWE	Fast, harmless	Expensive equipment
SWE	Measure tissues in vivo	Expensive equipment

ISSN: 1479-5876