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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Acidic ascites inhibits ovarian cancer cell proliferation and correlates with the metabolomic, lipidomic and inflammatory phenotype of human patients

Fig. 3

Polar and lipid metabolites levels in ovarian cancer ascites of stages II-III vs IV. A Volcano plot indicating statistically significant polar and lipid metabolites changes between the tumor stages: red and blue plots mean up and down regular in stage IV. B Bar plot of fold change (FC) of pola and lipid metabolites and cytokines, blue and yellow means upregulation and downregulation in stage IV. C Individual metabolite dot plots showing alanine, glutamine, isoleucine, phenylalanine,valine and 3-hydroxybutyrate concentration changes between tumor stages II-III and IV (* < 0.05, ** < 0.01). D Spearman plot of alanine, glutamine and phenylalanine with stages (p < 0.05)

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