Skip to main content
Fig. 2 | Journal of Translational Medicine

Fig. 2

From: An extensive bioinformatics study on the role of mitochondrial solute carrier family 25 in PC and its mechanism behind affecting immune infiltration and tumor energy metabolism

Fig. 2

Identification of a new classification of mitochondrial solute carrier family 25 (SLC25A) members and the construction of a prognostic risk model in PC. A Survival analysis revealed that the new classification had a good prognostic value in the TCGA-PAAD cohort. B The principal component analysis detected a partial overlap between clusters 1 and 2, and it did not distinguish well between PC patients based on the mRNA expression levels. C A new 5-signature prognostic model for PC based on DEGs of SLC25A members was developed using Lasso and Cox multifactor regression analysis. D In the TCGA-PAAD cohort, the new prognostic model demonstrated a significant prognostic value, which was verified in the ICGC-PAAD cohort. E The area under the curve (AUC) for 1-, 3-, and 5-year OS in the TCGA cohort was 0.72, 0.77, and 0.85, respectively, according to the Receiver Operating Characteristic (ROC) findings. Next, we assessed the model's predictive abilities in the ICGC-PAAD cohort, and the findings revealed improved predictive efficacy

Back to article page