Fig. 1

Preliminary investigation of mitochondrial solute carrier family 25 (SLC25A) members in PC. A Venn diagram depicting the interaction between SLC25A members and differentially expressed genes (DEGs) from the TCGA-PAAD cohort (Normal vs. Tumor). B In comparison to normal pancreatic tissues, 11 SLC25A members were downregulated and 27 SLC25A members were upregulated in the PC tumor tissues (C). The differential expression levels of 38 SLC25A members between different neoplasm histologic grades (1: well differentiation, 2: moderate differentiation, 3: poor differentiation, 4: undifferentiation), (⁻P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001). D High expression of SLC25A11, SLC25A29, and SLC25A44 was associated with longer patient survival in PC, according to Kaplan–Meier analysis