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Table 1 Respiratory parameters after ALI induction (left and right are separated; main study)

From: Unilateral acute lung injury in pig: a promising animal model

 

Immediately after ALI (0 h)

1 h after ALI

2 h after ALI

3 h after ALI

4 h after ALI

5 h after ALI

6 h after ALI

7 h after ALI

Left

Right

Left

Right

Left

Right

Left

Right

Left

Right

Left

Right

Left

Right

Left

Right

Compliance (Cdyn)

6.7 ± 2.1† (n = 5)

18.3 ± 2.3 (n = 5)

5.8 ± 2.4† (n = 6)

15.9 ± 4.3 (n = 6)

6 ± 2.4 (n = 4)

15.3 ± 2.6 (n = 4)

6.3 ± 2.6 (n = 4)

14.9 ± 1.5 (n = 4)

6.2 ± 2.5 (n = 3)

15.4 ± 4.8 (n = 3)

5.7 ± 3.9 (n = 3)

13.3 ± 4 (n = 3)

4.8 ± 3.4 (n = 4)

11.8 ± 2.7 (n = 4)

4.8 ± 3.4 (n = 4)

12.4 ± 3.4 (n = 4)

FiO2 (%)

0.4 ± 0.12 (n = 5)

0.38 ± 0.08 (n = 5)

0.49 ± 0.19 (n = 4)

0.49 ± 0.23 (n = 4)

0.44 ± 0.18 (n = 4)

0.46 ± 0.23 (n = 4)

0.44 ± 0.18 (n = 4)

0.44 ± 0.18 (n = 4)

0.35 ± 0.05 (n = 3)

0.35 ± 0.05 (n = 3)

0.4 ± 0.1 (n = 3)

0.45 ± 0.13 (n = 3)

0.48 ± 0.17 (n = 4)

0.5 ± 0.18 (n = 4)

0.47 ± 0.21 (n = 3)

0.55 ± 0.18 (n = 3)

Tidal volume (VT)

141 ± 42† (n = 5)

353 ± 60 (n = 5)

155 ± 54 (n = 4)

350 ± 22 (n = 4)

156 ± 41 (n = 4)

333 ± 21 (n = 4)

149 ± 28 (n = 4)

348 ± 18 (n = 4)

149 ± 47 (n = 3)

349 ± 12 (n = 3)

129 ± 82 (n = 3)

333 ± 16 (n = 3)

124 ± 71 (n = 4)

327 ± 18 (n = 4)

105 ± 92 (n = 3)

321 ± 5 (n = 3)

etCO2 (mmHg)

12.3 ± 7.1 (n = 4)

57.4 ± 12.2 (n = 5)

26.5 ± 30.4 (n = 2)

52.3 ± 3.2 (n = 3)

32 ± 19.8 (n = 2)

56.3 ± 5.5 (n = 3)

32.5 ± 27.6 (n = 2)

55 ± 8.5 (n = 3)

33 ± 36.8 (n = 2)

53.3 ± 11.9 (n = 3)

24.7 ± 24.1 (n = 3)

59 ± 5.3 (n = 3)

24.3 ± 24.2 (n = 4)

58.7 ± 10 (n = 3)

22 ± 28.3 (n = 2)

58.5 ± 13.4 (n = 2)

PEEP (cmH2O)

7 ± 2.2 (n = 5)

5.4 ± 0.6 (n = 5)

6.8 ± 2.5 (n = 4)

5.8 ± 0.5 (n = 4)

8 ± 0 (n = 4)

5.8 ± 0.5 (n = 4)

8 ± 0 (n = 4)

5.8 ± 0.5 (n = 4)

8 ± 0 (n = 3)

5.7 ± 0.6 (n = 3)

8 ± 0 (n = 3)

5.7 ± 0.6 (n = 3)

8 ± 0 (n = 4)

5.8 ± 0.5 (n = 4)

8 ± 0 (n = 3)

5.7 ± 0.6 (n = 3)

Ppeak (cmH2O)

30.5 ± 7.1 (n = 4)

30 ± 6.7 (n = 4)

32.7 ± 2.1 (n = 3)

26.3 ± 3.1 (n = 3)

34 ± 5.3 (n = 3)

28.3 ± 3.1 (n = 3)

34 ± 5.3 (n = 3)

29.3 ± 2.9 (n = 3)

32 ± 0 (n = 2)

29 ± 2.8 (n = 2)

32.5 ± 0.7 (n = 2)

30 ± 2.8 (n = 2)

35.3 ± 4.9 (n = 3)

31.7 ± 3.5 (n = 3)

37.5 ± 6.4 (n = 2)

32 ± 4.2 (n = 2)

Pplat (cmH2O)

29.6 ± 7.3 (n = 4)

27.5 ± 7.7 (n = 4)

32.7 ± 2.1 (n = 3)

25.3 ± 4.7 (n = 3)

33.7 ± 5.7 (n = 3)

27.7 ± 4.2 (n = 3)

34 ± 5.3 (n = 3)

28.7 ± 4 (n = 3)

32 ± 0 (n = 2)

27.5 ± 5 (n = 2)

32 ± 0 (n = 2)

28.5 ± 5 (n = 2)

35 ± 5.2 (n = 3)

30.7 ± 5.1 (n = 3)

37 ± 7.1 (n = 2)

30.5 ± 6.4 (n = 2)

Respiratory rate (RR)

21.8 ± 3.9 (n = 4)

27.3 ± 14.2 (n = 4)

20.7 ± 2.3 (n = 3)

25.3 ± 4.2 (n = 3)

20.7 ± 2.3 (n = 3)

25.3 ± 4.2 (n = 3)

21.3 ± 3.1 (n = 3)

24.7 ± 1.2 (n = 3)

22 ± 5.7 (n = 2)

24 ± 2.8 (n = 2)

22 ± 5.7 (n = 2)

27.5 ± 3.5 (n = 2)

23.3 ± 2.3 (n = 3)

24.7 ± 5 (n = 3)

24 ± 2 (n = 3)

24.7 ± 5 (n = 3)

I:E

1:1.3 ± 0.1 (n = 3)

1:1.5 ± 0.1 (n = 3)

1:1.2 (n = 1)

1:1.4 (n = 1)

1:1.2 (n = 1)

1:1.4 (n = 1)

1:1.2 (n = 1)

1:1.5 (n = 1)

1:1.2 (n = 1)

1:1.5 (n = 1)

1:1.2 (n = 1)

1:1.5 (n = 1)

1:1.2 (n = 1)

1:2 (n = 1)

1:1.2 (n = 1)

1:2 (n = 1)

  1. Values are expressed as mean ± SD
  2. FiO2: fraction of inspired Oxygen; PEEP: positive end-expiratory pressure; I:E: inspiratory time/expiratory time ratio; Ppeak: peak ventilatory pressure; Pplat: plateau pressure
  3. †p < 0.05
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Journal of Translational Medicine

ISSN: 1479-5876

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