Table 2 Parameters of systemic hemodynamics and oxygenation state between control and treatment groups*
From: Clinical improvement of sepsis by extracorporeal centrifugal leukocyte apheresis in a porcine model
|  |  | Baseline | 12 h | 18 h | 42 h | P’value |
|---|---|---|---|---|---|---|
MAP (mmHg) | Control | 125.6 ± 10.1b | 110.3 ± 17.6 | 93.2 ± 11.3 | 85.3 ± 16.3 | 0.015 |
Treatment | 130.5 ± 13.5a | 101.2 ± 13.7c | 99.2 ± 20.5 | 110.3 ± 9.5 | 0.049 | |
P value | 0.932 | 0.297 | 0.053 | 0.031 | – | |
HR (beats/minute) | Control | 103 ± 11.1ab | 112.6 ± 14.5 | 109.7 ± 20.3 | 130.6 ± 15.6 | 0.001 |
Treatment | 105 ± 8.6a | 120.1 ± 6.2c | 123.5 ± 12.5 | 100.3 ± 23.7 | 0.049 | |
P value | 0.438 | 0.683 | 0.044 | 0.015 | – | |
PH | Control | 7.5 ± 0.04 | 7.6 ± 0.04 | – | 7.5 ± 0.03 | 0.064 |
Treatment | 7.5 ± 0.02 | 7.5 ± 0.08 | 7.5 ± 0.03 | 7.5 ± 0.03 | 0.138 | |
P value | 0.543 | 0.021 | – | 0.551 | – | |
PaO2 (mmHg) | Control | 99.0 (94.8, 113.3)ab | 87.0 (77.5, 94.0) | – | 74.0 (69.5, 78.3) | 0.025 |
Treatment | 96.0 (86.5, 101.5)a | 75.5 (64.8, 82.8)c | 77.5 (72.3, 83.8) | 95.5 (92.3, 96.3) | 0.011 | |
P value | 0.310 | 0.092 | – | 0.003 | – | |
PaO2/FiO2 | Control | 521.4 ± 83.3ab | 390.3 ± 38.7 | – | 352.3 ± 20.9 | 0.000 |
Treatment | 447.6 ± 42.4a | 381.3 ± 50.7c | 369.1 ± 39.6 | 450 ± 12.3 | 0.003 | |
P value | 0.098 | 0.779 | – | 0.000 | – | |
PaCO2 (mmHg) | Control | 47.0 ± 4.2a | 45.0 ± 1.4c |  | 48.2 ± 1.7 | 0.049 |
Treatment | 46.8 ± 3.8b | 46.3 ± 6.2 | 46.0 ± 2.4 | 41.5 ± 2.1 | 0.003 | |
P value | 0.949 | 0.051 | – | 0.001 | – | |
Lac (mmol/L) | Control | 1.6 ± 0.7ab | 2.9 ± 0.5 | – | 3.1 ± 1.3 | 0.034 |
Treatment | 1.6 ± 0.2a | 3.3 ± 1.5c | 1.4 ± 0.4 | 1.2 ± 0.3 | 0.003 | |
P value | 0.868 | 0.112 | – | 0.008 | – |