From: Clinical improvement of sepsis by extracorporeal centrifugal leukocyte apheresis in a porcine model
 | Control group | Treatment group | P value |
---|---|---|---|
Weight (kg) | 54.4 ± 8.7 | 54.3 ± 11.3 | 0.995 |
Body length (cm) | 125.5 (124.0, 128.5) | 125.0 (124.0, 132.3) | 0.937 |
TBV (L) | 2.8 ± 0.5 | 2.8 ± 0.5 | 1 |
MAP (mmHg) | 125.6 ± 10.1 | 130.5 ± 13.5 | 0.932 |
HR (beats/minute) | 103 ± 11.1 | 105 ± 8.6 | 0.438 |
Blood cells | |||
 Leukocyte (*10^9/L) | 15.6 ± 1.5 | 14.2 ± 3.1 | 0.394 |
 Hemoglobin (g/L) | 104.0 ± 13.2 | 99.7 ± 12.4 | 0.611 |
 Hct (%) | 30.8 ± 4.4 | 33.6 ± 3.9 | 0.327 |
 Platelet (*10^9/L) | 365.75 ± 107.0 | 367.5 ± 138.0 | 0.984 |
 B Cell (%) | 3.6 ± 1.1 | 3.5 ± 1.5 | 0.947 |
 DC Cell (%) | 4.2 ± 1.5 | 4.2 ± 1.5 | 0.997 |
 Th cell (%) | 4.0 ± 2.7 | 6.9 ± 4.2 | 0.271 |
 Tc cell (%) | 7.5 ± 1.5 | 13.1 ± 5.6 | 0.093 |
 Th/Tc cells (%) | 51.9 ± 25.5 | 56.9 ± 36.8 | 0.822 |
 Monocyte (%) | 1.9 (1.6, 2.4) | 2.3 (1.8, 4.2) | 0.310 |
 Neutrophil (%) | 48.6 ± 3.8 | 42.6 ± 8.1 | 0.210 |
Hepatic and renal function | |||
 ALT (U/L) | 82.0 ± 64.2 | 105.0 ± 78.4 | 0.640 |
 AST (U/L) | 33.5 (28.0, 64.5) | 36.5 (31.8, 60.5) | 0.485 |
 TBIL (μmol/L) | 1.9 ± 1.1 | 1.5 ± 1.0 | 0.531 |
 DBIL (μmol/L) | 0.4 ± 0.2 | 0.3 ± 0.3 | 0.629 |
 IBIL (μmol/L) | 1.5 ± 1.0 | 1. 2 ± 0.8 | 0.562 |
 Alb (g/L) | 23.3 ± 6.3 | 24.0 ± 2.7 | 0.807 |
 Creatine (μmol/L) | 94.5 ± 19.2 | 91.5 ± 20.9 | 0.825 |
 Urea (mmol/L) | 3.1 ± 1.0 | 2.6 ± 0.6 | 0.359 |
Blood gas assay | |||
 PH | 7.5 ± 0.04 | 7.5 ± 0.02 | 0.543 |
 PaO2 (mmHg) | 99.0 (94.8, 113.3) | 96.0 (86.5, 101.5) | 0.310 |
 PaCO2 (mmHg) | 47.0 ± 4.2 | 46.8 ± 3.8 | 0.949 |
 PiO2/FiO2 (mmHg) | 521.6 ± 83.3 | 447.6 ± 42.6 | 0.098 |
 Lac (mmol/L) | 1.6 ± 0.7 | 1.6 ± 0.2 | 0.868 |