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Table 1 Baseline variables between control and treatment groups*

From: Clinical improvement of sepsis by extracorporeal centrifugal leukocyte apheresis in a porcine model

 

Control group

Treatment group

P value

Weight (kg)

54.4 ± 8.7

54.3 ± 11.3

0.995

Body length (cm)

125.5 (124.0, 128.5)

125.0 (124.0, 132.3)

0.937

TBV (L)

2.8 ± 0.5

2.8 ± 0.5

1

MAP (mmHg)

125.6 ± 10.1

130.5 ± 13.5

0.932

HR (beats/minute)

103 ± 11.1

105 ± 8.6

0.438

Blood cells

 Leukocyte (*10^9/L)

15.6 ± 1.5

14.2 ± 3.1

0.394

 Hemoglobin (g/L)

104.0 ± 13.2

99.7 ± 12.4

0.611

 Hct (%)

30.8 ± 4.4

33.6 ± 3.9

0.327

 Platelet (*10^9/L)

365.75 ± 107.0

367.5 ± 138.0

0.984

 B Cell (%)

3.6 ± 1.1

3.5 ± 1.5

0.947

 DC Cell (%)

4.2 ± 1.5

4.2 ± 1.5

0.997

 Th cell (%)

4.0 ± 2.7

6.9 ± 4.2

0.271

 Tc cell (%)

7.5 ± 1.5

13.1 ± 5.6

0.093

 Th/Tc cells (%)

51.9 ± 25.5

56.9 ± 36.8

0.822

 Monocyte (%)

1.9 (1.6, 2.4)

2.3 (1.8, 4.2)

0.310

 Neutrophil (%)

48.6 ± 3.8

42.6 ± 8.1

0.210

Hepatic and renal function

 ALT (U/L)

82.0 ± 64.2

105.0 ± 78.4

0.640

 AST (U/L)

33.5 (28.0, 64.5)

36.5 (31.8, 60.5)

0.485

 TBIL (μmol/L)

1.9 ± 1.1

1.5 ± 1.0

0.531

 DBIL (μmol/L)

0.4 ± 0.2

0.3 ± 0.3

0.629

 IBIL (μmol/L)

1.5 ± 1.0

1. 2 ± 0.8

0.562

 Alb (g/L)

23.3 ± 6.3

24.0 ± 2.7

0.807

 Creatine (μmol/L)

94.5 ± 19.2

91.5 ± 20.9

0.825

 Urea (mmol/L)

3.1 ± 1.0

2.6 ± 0.6

0.359

Blood gas assay

 PH

7.5 ± 0.04

7.5 ± 0.02

0.543

 PaO2 (mmHg)

99.0 (94.8, 113.3)

96.0 (86.5, 101.5)

0.310

 PaCO2 (mmHg)

47.0 ± 4.2

46.8 ± 3.8

0.949

 PiO2/FiO2 (mmHg)

521.6 ± 83.3

447.6 ± 42.6

0.098

 Lac (mmol/L)

1.6 ± 0.7

1.6 ± 0.2

0.868

  1. *Both the control and treatment group were induced sepsis after baseline evaluation
  2. TBV total blood volume, MAP mean arterial blood pressure, HR heart rate, Hct hematocrit, DC cell dendritic cell, Th cell T helper cell, Tc cell cytotoxic T cell, ALT alanine transaminase, AST aspartate aminotransferase, TBIL total bilirubin, DBIL direct bilirubin, IBIL indirect bilirubin, Alb albumin, PH pondus hyrogenil, PaO2 partial pressure of arterial oxygen, PaCO2 partial pressure of arterial carbon dioxide, SaO2 oxyhemoglobin saturation, Lac lactate